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Treatment |
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Treatment of
restless legs syndrome involves identifying the cause of
symptoms when possible. Pharmacotherapy involves dopamine |
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agonists which
are first line drugs for daily restless legs syndrome;
gabapentin and opioids can be used for treatment resistant
cases. |
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The dopamine
agonists pergolide, pramipexole, ropinirole, and cabergoline
are preferred over levodopa as levodopa has problems of |
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commonly having
a rebound effect. An algorithm for treating primary RLS (i.e.,
RLS that is not the result of another medical condition) |
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was created by
leading researchers at the Mayo Clinic and is endorsed by the
Restless Legs Syndrome Foundation. This document |
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provides
guidance to both the treating physician and the patient, and
includes both nonpharmacological and pharmacological |
| |
treatments.
Treatment of primary RLS should not be considered until
possible precipitating medical conditions are ruled out,
especially |
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venous
disorders. Drug therapy in RLS is not curative and is known to
have side effects such as nausea, dizziness, hallucinations, |
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orthostatic
hypotension, and sudden sleep attacks during the daytime. In
addition, it can be expensive, and thus it needs to be |
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considered with
caution. |
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|
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Secondary RLS
has the potential for cure if the precipitating medical
conditions, anaemia, venous disorder, etc., are managed
|
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effectively. In
many instances the alleged secondary conditions might be the
only conditions causing the RLS; these include iron
|
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deficiency,
varicose veins, and thyroid problems. Karl Ekbom in his
original thesis on RLS in 1945 had suspected venous disease in
about |
| |
12.5% of the
cases he studied. But due to the unavailability of Doppler
ultrasound imaging technology (the diagnostic tool that
detects |
| |
the abnormal
blood flow in the veins, "Venous Reflux", the pathological
basis for varicose veins) at that time, Ekbom may have |
| |
underestimated
the role of venous disease. In uncontrolled prospective
series, improvement of RLS was achieved in a high percentage |
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of patients who
had presented with a combination of RLS and venous disease and
had sclerotherapy or other treatment for the |
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correction of
venous insufficiency. |
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|
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Stretching
and shaking legs |
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Stretching the
muscles in the legs can bring instant and permanent relief,
lasting several days or longer. This does not work for
|
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everyone: |
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sometimes relief
is temporary, and discomfort can return within the span of a
few seconds. One stretching method consists of bending |
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over from a
standing position and reaching out one's hands to the ground
(touching the toes if possible). This position is held for 10
to |
| |
20 seconds and
repeated 3 times. |
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